Micrometastasis: Neglected enough!

Leishmania (Viannia) naiffi: rare enough to be neglected?

In the Brazilian Amazon, American tegumentary leishmaniasis (ATL) is endemic and presents a wide spectrum of clinical manifestations due, in part, to the circulation of at least seven Leishmania species. Few reports of Leishmania (Viannia) naiffi infection suggest that its occurrence is uncommon and the reported cases present a benign clinical course and a good response to treatment. This study...

Genetic determinants of lung cancer micrometastasis.

A Mathematical Model of a Micrometastasis MALCOLM

Experimental evidence indicates that tumour metastases can exist for long periods in a dormant state, with cell proliferation balancing cell death. However, this balance can be upset, by removing the primary tumour for instance, which causes the metastasis to grow, or by administering a substance inhibiting angiogenesis which causes the metastasis to regress. A mathematical model is presented f...

Classification of isolated tumor cells and micrometastasis.

BACKGROUND. Findings of isolated (disseminated or circulating) tumor cells (ITC) by immunocytochemistry and molecular pathology methods have led to varied interpretations and different applications of the TNM system. METHODS. An analysis of the relevant literature was undertaken. In addition, optional proposals for the classification of ITC, micrometastasis, and cytologic results in pleural and...

Neglected Population, Neglected Right

The laws, language, and tools of human rights have been instrumental in expanding access to lifesaving treatment for people living with HIV. Children, however, remain a neglected population, as evidenced by inadequate child-specific and child-friendly HIV treatment options. In this article, we explore the right to science, a potentially powerful but underdeveloped right in international law, an...